If this processing requires CYP3A4 (part of the larger CYP450 system), then CBD can inhibit the reaction, leaving too little active drug in the body for the desired effect.
Case in point: Codeine that is metabolized into morphine.
Vyvanse and Concerta are two other pharmaceutical medications, meant for ADHD,which also fall under this category.
Cannabis is becoming quite popular as a safe and natural medicine, with virtually zero toxicity. Research has rated this cannabinoid as least dangerous substance, when compared to substances such as alcohol and nicotine in regards to toxicity.
But the question is: Is CBD a natural food supplement or a medicine? Most discussions relating to its legal status depends on that, since “medicinal drugs are considered unsafe until proven safe” while it is just the opposite in case of natural supplements. (8)
Additionally, CBD oil is still unregulated, meaning its correct dosage is still unknown. However, human studies have indicated that CBD is quite very well tolerated even up to a daily dose of 1,500 mg (9).
Cannabidiol is comparatively safe when consumed in appropriate doses among adults. (10)